Conquering Lyme Disease

Science Bridges the Great Divide

Brian A. Fallon, MD, and Jennifer Sotsky, MD

Columbia University Press

Conquering Lyme Disease

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Pub Date: December 2017

ISBN: 9780231183840

456 Pages

Format: Hardcover

List Price: $30.00£24.95

Pub Date: December 2017

ISBN: 9780231545181

456 Pages

Format: E-book

List Price: $29.99£24.95

Conquering Lyme Disease

Science Bridges the Great Divide

Brian A. Fallon, MD, and Jennifer Sotsky, MD

Columbia University Press

Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online.

In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.
A lucid and important book, filled with moving case histories and vignettes, about an infectious illness that is threatening many lives. Siddhartha Mukherjee, author of The Emperor of All Maladies: A Biography of Cancer and The Gene: An Intimate History
Lyme disease is a more complicated and nuanced illness than has been previously recognized. Fallon and Sotsky’s experience with the neuropsychological manifestations of Lyme, combined with their insights into the current patient experience, make this book a significant addition to the literature. A well-organized, comprehensive treatment of Lyme disease and the associated issues that patients face. John Aucott, director, Johns Hopkins Lyme Disease Clinical Research Center
Conquering Lyme Disease is a balanced and factual synthesis of what is known and unknown about Lyme disease. Written in a clear and understandable way for a lay audience as well as medical professionals, it is a rich source of information on this complex subject, explaining the science behind current treatments and future directions for research. Stephen W. Barthold, University of California, Davis
An enlightening, informative, and up-to-date account of the key issues surrounding the complexity, controversy, prevention, diagnosis and treatment of Lyme borreliosis, especially the persistent form of the disease. Written by an outstanding and well-respected physician with tremendous experience, Conquering Lyme Disease will help to bridge the great divide and offer new hope in our fight against this debilitating disease A must read for all interested in Lyme and associated diseases. Ying Zhang, MD, Johns Hopkins University, Bloomberg School of Public Health
Acknowledgments
Preface
What Are Common Terms?
1. What Is Lyme Disease?
2. The Early History and Epidemiologic Surveillance
3. What Are the Symptoms and Signs of Lyme Disease?
4. What Do the Diagnostic Tests Tell Us?
5. The Great Divide and the Lyme Wars
6. Why Would Symptoms Persist After Antibiotic Treatment?
7. What Are the Treatments for Lyme Disease?
8. Other Tick-borne Infections
9. What Other Non-infectious Diseases Have Lyme-like Symptoms?
10. Lyme Disease Prevention and Transmission
11. Suggestions to the Patient Seeking Evaluation or Treatment
12. The Experience of the Patient with Chronic Symptoms
13. Frequently Asked Questions
14. The Good News Emerging from Lyme Disease Research
Appendix: Generic (Brand) Drug Names
Glossary of Terms
References
Index

About the Author

Brian A. Fallon, MD, is director of the Lyme and Tick-Borne Diseases Research Center at the Columbia University Medical Center.

Jennifer Sotsky, MD, is a physician with a specialty in narrative medicine. She is a resident at Columbia University Medical Center.